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diagnosis differential hematology management oncology aafp acute aplastic approach celiac chronic classification cobalamin deficiency disease dysfunction elevatedmcv hiv hyposmia macrocytic
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Fatigue and IBD ... , Anemia • Prevalence ... Crohn's > UC Anemia ... /other causes • ... #IBD #Algorithm
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Pernicious Anemia ... • Small Bowel Disorder ... • Pernicious Anemia ... #Macrocytic #Anemia
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Inflammatory: • IBD ... • Rheumatic disorders ... effect following treatment ... Iron deficiency anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Deficiency • B12 ... Deficiency • Aplastic Anemia ... • Anemia of Chronic ... Non-lmmune #Anemia
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... autoantibodies (pernicious anemia ... Worsening macrocytic anemia ... wt loss • If anemia ... - CBC, PBS - anemia
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Differential Diagnosis Algorithm ... Hematologic • Anemia ... • Somatization Disorder ... #causes
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
Iron-deficiency anemia ... unresponsive to treatment ... without discernable cause ... Inflammatory (IBD ... #gastroenterology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Anemia is described ... hemoglobin of less than 12 ... that involves disorders ... These causes could
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Presentation: • Fever • Fatigue ... and petechiae Causes ... Treatment:
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Anemia • Aplastic ... Anemia • Bone ... Megaloblastic Anemia ... Myelophthisic Anemia
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