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diagnosis differential hematology management aafp anosmia approach celiac classification cobalamin deficiency disease dysfunction hyposmia mds myelodysplasia myelodysplastic nutrition oncology pouchitis
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Fatigue and IBD ... , Anemia • Prevalence ... Crohn's > UC Anemia ... /other causes • ... #IBD #Algorithm
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Inflammatory: • IBD ... • Rheumatic disorders ... effect following treatment ... Iron deficiency anemia
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Hematologic • Anemia ... • Somatization Disorder ... #Chronic #Fatigue ... #causes
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... RBCs on Smear • Chronic ... Deficiency • B12 ... • Anemia of Chronic ... #Causes #Hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... dysfunction, and/or disorders ... slowing, neuropathy, fatigue ... diarrhea related to IBD ... Check for IF ab Treatment
Anosmia Causes - Principal Etiologies of Olfactory Dysfunction For olfactory disorders (and for most taste problems), the
Anosmia Causes - ... disorders (and ... polyps) as the cause ... improve after treatment ... these conditions.12
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 Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
Iron-deficiency anemia ... unresponsive to treatment ... without discernable cause ... Inflammatory (IBD ... #gastroenterology
Acute Pouchitis - Management Algorithm Ciprofloxacin 500 mg/12 h or metronidazole 20 mg/kg/d x 2 weeks -
Pouchitis - Management Algorithm ... Ciprofloxacin 500 mg/12 ... - No Response (Chronic ... #treatment #IBD ... #gastroenterology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Symptoms: • Fatigue ... Marrow Failure • Chronic ... Neutropenia • Platelet Disorders ... Nutritional: vitamin B12
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