64 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
suspect underlying hematologic ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... diagnosis #management #algorithm
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
Marrow Failure Syndromes ... Telemore Biology Disorders ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes ... #diagnosis #Hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Diagnostic Algorithm ... disease - Vitamin B12 ... Probable bone marrow disorder ... Underproduction #Algorithm ... #hematology #diagnosis
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Differential Diagnosis Algorithm ... Toxins • Aplastic Anemia ... deficiency: • B12 ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Differential Diagnosis Algorithm ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Differential Diagnosis Algorithm ... • Rheumatic disorders ... effect following treatment ... Iron deficiency anemia ... #Causes #Hematology
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic Anemia ... • 812, Folate ... #Macrocytic #Anemia ... differential #diagnosis #algorithm ... #hematology #workup
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Deficiency • B12 ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... #Causes #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Autoimmune Diseases: • Systemic ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #hematology