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diagnosis differential management systemic dermatology generalized rheumatology aplastic cerebritis classification elevatedmcv erythematosus hodgkins leukemia lupus lymphoma macrocytic macrocytosis mds myelodysplasia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Differential Diagnosis Algorithm ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... renal failure/uremia ... Myelodisplastic syndrome ... #primary #secondary ... #causes
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... , Seizure disorders ... autoantibodies that will cause ... APS), Secondary
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... • Nephrotic syndrome ... #Diagnosis #Algorithm ... #causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... renal failure/uremia ... Myelodisplastic syndrome ... #secondary #systemic ... #causes
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... Chediak-Higashi syndrome ... drug reactions - Secondary ... Megaloblastic anemia-rare ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... Nutritional: vitamin B12 ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - Parvovirus B19 ... • Parvovirus B19 ... Treatment: ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
sweats, bleeding • Pruritis ... - infiltrates (anemia ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Cryoglobulinemia (4%-12% ... Adenocarcinoma Treatment
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