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diagnosis differential management neurology oncology rheumatology b1 cobalamin encephalopathy low pathophysiology thiamine algorithm alkaline alp aplastic atrophicglossitis behcet bronchiectasis candida
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Vitamins and Vitamin Deficiency ... Wernicke-Korsakoff syndrome ... #Vitamins #Deficiency ... differential #diagnosis #signs ... #symptoms #nutrition
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
• Chronic alcoholism ... Anorexia nervosa Treatment ... can improve symptoms ... development of Korsakoff syndrome ... (chronic B1 deficiency
Risk Factors and Signs of Copper Deficiency Risk Factors: • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
of Copper Deficiency ... bowel disease, Chronic ... diarrhoea, Short bowel syndrome ... dental fixatives, Treatment ... #riskfactors #symptoms
Causes of Low Vitamin B12 Levels Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people Autoimmune
of Low Vitamin B12 ... Levels Low vitamin B12 ... and Sjögren's syndrome ... antagonists #VitaminB12 ... #deficiency #low
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
• Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
of chronic kidney ... Megaloblastic: Vitamin B12 ... deficiency • ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency Wernicke's encephalopathy is a neurological condition due to longstanding
- Thiamine Deficiency ... thiamine (vitamin B1 ... due to chronic ... and retrograde amnesia ... #vitaminB1 #B1 #
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Chronic abuse of ... N2O can cause a syndrome ... deficiency. ... of pernicious anemia ... #NitrousOxide #VitaminB12
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
autoantibodies (pernicious anemia ... malabsorption syndromes ... #VitaminB12 #deficiency ... differential #diagnosis #hematology ... #nutrition
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... Treatment: ... • Improve the symptoms ... #oncology #hematology
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