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diagnosis differential management rheumatology algorithm causes dermatology oncology hepatology workup deficiency systemic disease nephrology signs symptoms lupus nutrition classification erythematosus
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Marrow Failure Syndromes ... with Pancytopenia ... lauraebrown #Pancytopenia ... #Syndromes #BoneMarrow ... #diagnosis #Hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Neutropenia with Pancytopenia ... and non-hematologic ... Toxins • Aplastic Anemia ... deficiency: • B12 ... deficiencies #Pancytopenia
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... HLH syndrome 5. ... Acquired Aplastic Anemia ... marrow failure syndrome ... Diagnosis #Algorithm #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bone marrow + pancytopenia ... - Parvovirus B19 ... • Peripheral Pancytopenia ... Treatment: ... #oncology #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... diagnosis #management #treatment ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... HLH syndrome 5 ... Acquired Aplastic Anemia ... marrow failure syndrome ... Diagnosis #Algorithm #Hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is ... a hematologic condition ... hemoglobin of less than 12 ... The etiology of pancytopenia
Medications for the Management of Anemia TREATMENT OF ANEMIA - Cyanocobalamin/B12 - Erythropoietin/epoetin alfa - Darbepoetin alfa
Management of Anemia ... TREATMENT OF ... /B12 - Erythropoietin ... acid - Iron TREATMENT ... #Pharmacology #Treatment
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Low Serum B12 ... - Low Serum B12 ... Myelodysplastic Syndromes ... • Rule out B12 ... Algorithm #Causes #Hematology
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