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diagnosis management erythematosus lupus syndrome anthracycline behcet cardiomyopathy cardiotoxicity chemotherapy chronic cll hematology hemophagocytic her2 hlh leukemia lymphocytic lymphohistiocytosis peripartum
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Treatment: • ... #Summary #diagnosis ... #rheumatology #
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management Summary ... life-threatening • Treatment ... Evolution: Chronic disease ... #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... Cancer affecting ... cells can indicate disease ... microglobulin Treatment ... diagnosis #workup #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
B-LNH), solid cancers ... • Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... #summary #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... oral ulcers in 12 ... Oral aphthae : SLE ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Central nervous system ... Cryoglobulinemia (4%-12% ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Cardiomyopathy - Summary ... LV thrombus, RV systolic ... orthopnea, PND, LE ... diagnosis #management #cardiology ... #treatment
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
) and initiate treatment ... renin-angiotensin-aldosterone system ... severe valvular disease ... Cardiotoxicity #cardiology ... #oncology #pharmacology
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