12 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
infection Malar ... rash • SLE ... infection • Lyme ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Neurological 12% ... Other auto-immune, Infectious ... Lupusreference #SLE ... autoantibodies #signs ... #differential #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... extramedullary disease ... , bleeding, infections ... bruising, bleeding, infection ... #Hematology #Oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... Arthritis: • Joint pain ... Hodgkin lymphoma and leukemia
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... Physical Exam/Signs ... cells can indicate disease ... microglobulin Treatment ... diagnosis #workup #oncology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
noninflammatory Signs ... - Autoimmune Rheumatologic ... • Parvovirus B19 ... arthritis • SLE ... Symmetrical: • RA • SLE
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Episcleritis Signs ... ’s syndrome - Lupus ... Treatment: - Systemic ... #dermatology #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... Nonsurgical abdominal pain ... diagnosis #management #signs ... #symptoms #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... erythematosus [SLE ... ], AOSD) • Infection ... Treatment: • Corticosteroids ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
such as systemic lupus ... to exclude are infections ... purpura: strong sign ... vasculitis, and SLE ... differential #diagnosis #rheumatology