35 results
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Utilizing Uric Acid ADH ... Uric Acid - Low ... Uric Acid → SIADH ... #nephrology #sodium ... #low #uricacid
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia Algorithm ... Hyponatremia: • ADH ... OFF (UNa > 30): SIADH ... Primary polydipsia, Low ... #diagnosis #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... restriction alone in SIADH ... Present (Uosm ≥100): SIADH ... , Renal Sodium loss ... can be high or low
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Salt Wasting vs SIADH ... Neurological event 2) Sodium ... Hypovolaemia → ADH ... #SaltWasting #SIADH
Hyponatremia - Differential Diagnosis Algorithm
ADH Independent:
 • Tea and Toast Syndrome, Beer Potomania - Low solute
Differential Diagnosis Algorithm ... ADH Independent ... Beer Potomania - Low ... ADH Dependent: ... insufficiency, SIADH
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Differential Diagnosis Algorithm ... • UOsm > 300 - ADH ... - Appropriate ADH ... , SSRIs) - SIADH ... diagnosis #nephrology #sodium
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
the total body sodium ... osmolality, urine sodium ... stimulated in states of low ... activated in states of low ... EBV #potomania #SIADH
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
Inappropriate ADH ... secretion (SIADH ... insufficiency ADH ... Table #Causes #Sodium
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... overload Urea powder ... promoting passive sodium ... antagonists: • Blocks ADH ... SatyaPatelMD #SIADH
True Hyponatremia Differential Algorithm

Instead (or in addition) of volume status examination, check urine sodium and serum
Hyponatremia Differential Algorithm ... acid: - Urine sodium ... low, uric acid ... and uric acid low ... #Differential #Algorithm