61 results
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
: • MOA: Block ... : • MOA: Block ... primarily) and block ... : • MOA: Block ... #Classes #pathophysiology
Bradycardia Diagnostic and Management Algorithm

CONSIDER ETIOLOGY (not inclusive): 
 - STRUCTURAL: sick sinus, AV block, ischemia,
and Management Algorithm ... sick sinus, AV block ... Hypothyroidism - TOX: beta-blockers ... LIFE THREATENING CAUSES ... TREATMENT - Drugs (beta-blockers
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
: • MOA: Block ... : • MOA: Block ... primarily) and block ... : • MOA: Block ... #Classes #pathophysiology
Summary of Heart Blocks
1st Degree Heart Block:
 • Prolonged PR >200ms (5 small squares).
 • Narrow
Summary of Heart Blocks ... 1st Degree Heart Block ... Mobitz I Heart Block ... • Block in AV ... HeartBlocks #Types #Classification
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... cells: Insulin, Beta-Agonist ... #causes #potassium ... #low #pathophysiology
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
inhibitors Other causes ... Ketoconazole Low ... - NSAlDs - Beta-Blockers ... #Hyperkalemia #Algorithm ... #differential #causes
Shock - Differential Diagnosis by Classification
Reflex Syncope 
 - Vasovagal syncope
   • Prolonged standing
Differential Diagnosis by Classification ... • AV block ... side effect (e.g. αblockers ... Differential #Diagnosis #Classification ... #Table #Causes
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis:
https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext

#Pathophysiology #Mechanism #Nephrology
How SGLT2 inhibitors ... block glucose reabsorption ... -4/fulltext #Pathophysiology
Supraventricular Tachycardia (SVT) - Differential Diagnosis Framework and Management

Regular SVT: Sinus Tachycardia, AVNRT, AVRT, Atrial Flutter,
AFIb w/ variable block ... Ask patient to blow ... Normotensive: Beta-Blocker
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
malignant, pediatric cases ... hypotension (may reflect low ... phenoxybenzamine blocks ... Starting beta blockers ... • Beta blockers