17 results
Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Classification - Summary Table ... this class are beta ... blockers.⠀ Class ... III agents - Potassium ... Classification #Summary #Table
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • Recent IV potassium ... • Beta blockers ... cell membrane - Beta ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • Recent IV potassium ... • Beta blockers ... cell membrane - Beta ... #high #nephrology
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management Algorithm ... Dialysis Serum potassium ... #hyperkalemia #potassium ... #high #diagnosis ... #management #algorithm
Modified penicillin binding proteins as mechanism of resistance to antibiotics.
Penicillin Binding Proteins (Transpeptidases) cross link peptidoglycan
Penicillin Binding ... the cell wall - Beta-lactam ... active site and block ... - Vancomycin blocks ... antibiotic (e.g. high
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
transplant - SLE High ... - NSAlDs - Beta-Blockers ... #Hyperkalemia #Algorithm
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
works by directly binding ... - When digoxin blocks ... Hyperkalemia (high ... potassium levels ... Since digoxin blocks
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Hyperkalemia Treatment Algorithm ... bradycardia, AV blocks ... Combo of insulin + beta-agonist ... glucose <100 • Beta-agonist ... treatment Remove potassium
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... patients sensitive to high ... of aspiration #Potassium ... #Binding #Hyperkalemia ... #pharmacology #table
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Differential Diagnosis Algorithm ... • ENaC blockers ... • Obstruction High ... nephropathy • Beta ... Differential #Diagnosis #Algorithm