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diagnosis symptoms signs management differential pharmacology cardiology endocrinology nephrology syndrome clinical hepatology infectiousdiseases causes algorithm msk complications gastroenterology hematology parasite
COVID-19 Life Cycle #COVID19 #LifeCycle #Timeline #Pathophysiology #Diagnosis
Cycle #COVID19 #LifeCycle ... #Timeline #Pathophysiology
Mechanism of Action of Bile Acid Sequestrants Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action of Bile ... Sequestrants Bile ... Sequestrants → ↓ Hepatic Bile ... Pool → ↑ Hepatic Bile ... sequestration #pathophysiology
Biochemistry and Metabolism of Bilirubin Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
Excreted into bile ... ducts and common bile ... Biochemistry #Metabolism #pathophysiology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
membrane (NOT within bile ... stimulated by bile ... bilirubin into bile ... Bilirubin #Hepatology #Pathophysiology
Plasmodium falciparum life cycle 1: Mosquito bite, transmission of sporozoite 2: Liver, Asexual replication. 1 sporozoite → 10-30,000
cycle 1: Mosquito bite ... Plasmodium #falciparum #lifecycle
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Biliary Cirrhosis - Pathophysiology ... relative with PBC Pathophysiology ... gradual loss of bile ... Biliary #Cirrhosis #Pathophysiology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Biliary tree or bile ... abnormality vs bone Bili
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... small intralobular bile ... of intralobular bile ... of interlobular bile ... related disease, Bile
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
disease US — Normal Bile ... US - Dilated Bile ... Ducts • Common Bile
Bile acids are the end products of cholesterol catabolism. Cholic acid and chenodeoxycholic acid are the
Bile acids are the ... major primary bile ... secretion into bile ... 200 to 600 mg bile ... 5% of a total bile
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