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Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
non-ICU vs ICU causes ... Hyperbilirubinemia #direct #bilirubin ... gastroenterology #hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
birth with serum bilirubin ... associated with bilirubin ... and stress may cause ... in conjugated bilirubin ... #hepatology #diagnosis
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... brown: elevated bilirubin ... chylous ascites), bilirubin ... Differential #Diagnosis #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
hepatorenal syndrome Clues ... function: INR, bilirubin ... Post-Hepatic: • Cardiac causes ... Differential #Diagnosis #causes ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... hepatocellular injury • Bilirubin ... week • Direct bilirubin ... Elevation: • Bilirubin ... diagnosis #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... slightly elevated • Bilirubin ... diagnosis #workup #hepatology
Bilirubin Metabolism - Pathophysiology • Conjugated Bilirubin • Unconjugated Bilirubin By Dr. Khushboo Gala @LouLectures #Bilirubin #Metabolism #Pathophysiology
Bilirubin Metabolism ... • Conjugated Bilirubin ... • Unconjugated Bilirubin ... LouLectures #Bilirubin ... Pathophysiology #hepatology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Algorithm and Causes ... Increased Serum bilirubin ... #Differential #Causes ... #Workup #Hematology
Biochemistry and Metabolism of Bilirubin Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
Metabolism of Bilirubin ... → Unconjugated Bilirubin ... "indirect bilirubin ... and "indirect" bilirubin ... pathophysiology #hepatology
Approach to Neonatal Jaundice Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Neonatal Jaundice Causes ... (1) increased bilirubin ... , (2) impaired bilirubin ... or (3) impaired bilirubin
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