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diagnosis causes algorithm clinical management cardiology nephrology table pulmonary radiology neurology hematology dermatology pocus mnemonic pathophysiology hepatology workup ddxof infections
Localized skin infections and associations: Cellulitis, Bite wounds, Ulcers, Nodules, Eschars #SSTIs #associations #SkinInfections #cellulitis #ulcer #eschar #bites #nodules #differential #diagnosis #infectiousdisease
associations: Cellulitis, Bite ... ulcer #eschar #bites ... #nodules #differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... US - Dilated Bile ... Ducts • Common Bile ... Duct Stone • Biliary ... #LiverEnzymes #Differential
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
genes coding for bile ... Dysfunction - Biliary ... certain drugs, biliary ... external pressure on bile ... #unconjugated #differential
Mechanism of Action of Bile Acid Sequestrants Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action of Bile ... Sequestrants Bile ... Sequestrants → ↓ Hepatic Bile ... Pool → ↑ Hepatic Bile ... Plasma LDL-C #biliary
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Drugs - Primary biliary ... PSC - Other biliary ... diseases/Bile duct ... ALP #Elevation #Differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... of intralobular bile ... No extrahepatic biliary ... ducts Differential ... malignancy #Primary #Biliary
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... • US - Normal Bile ... • US - Dilated Bile ... - CBD stone, Biliary
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... gradual loss of bile ... inflammation and biliary ... #PBC #Primary #Biliary
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
hepatitis - Acute biliary ... Hemochromatosis - Primary biliary ... Acute #Causes #Differential
Alpha-gal Syndrome (AGS) - Diagnosis Algorithm Does patient have recurrent episodes of urticaria, angioedema or isolated GI
- Known tick bites ... irritation at site ... of tick bite •
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