32 results
diagnosis hepatology differential primary causes lfts pbc management cholangitis cirrhosis infectiousdiseases injury abnormal ascites bile cdc elevation lifecycle metabolism parasite
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... US - Dilated Bile ... Duct Stone • Biliary ... Differential #Diagnosis #Algorithm
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary Biliary ... Cholangitis #pathophysiology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... PSC - Other biliary ... diseases/Bile duct
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Extrahepatic - Biliary ... Choledocholithiasis, Biliary ... - Obstruction: Biliary ... differential #diagnosis #algorithm
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... cholestasis → Cirrhosis/Liver ... No extrahepatic biliary ... or higher • Liver
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... • US - Normal Bile ... - CBD stone, Biliary ... Transaminitis #Algorithm
Mechanism of Action of Bile Acid Sequestrants Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action of Bile ... Sequestrants Bile ... Pool → ↑ Hepatic Bile ... Plasma LDL-C #biliary ... sequestration #pathophysiology
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... gradual loss of bile ... inflammation and biliary ... #PBC #Primary #Biliary
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute Liver ... Hepatocellular - Liver ... hepatitis, Acute biliary ... Extrahepatic • Biliary ... Causes #Acute #algorithm
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... specific for the liver ... ALP - Biliary ... tree or bile flow ... SinaiBmoreIMRes #Liver
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