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hematology management oncology hemeonc latenttb tb tuberculosis algorithm chronic classification cll differential disorders emergencies eosinophil eosinophilia hemophagocytic hlh hodgkins leukemia
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... /µL Workup • Screen ... glucocorticoid treatment ... organ-specific signs ... #Differential #diagnosis
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
involvement - seeding ... Tuberculosis Diagnosis ... Tuberculosis Treatment ... Tuberculosis #TB #Diagnosis ... #Management #Treatment
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
involvement - seeding ... Tuberculosis Diagnosis ... Tuberculosis Treatment ... Tuberculosis #TB #Diagnosis ... #Management #Treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... phenomenon CLL Diagnosis ... microglobulin Treatment ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... unusual bruising or bleeding ... are caused by bleeding ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... • PET scan - activity ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... Hodgkins #lymphoma #diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... Adenocarcinoma Treatment ... muscarinic agonists • Active ... Sjogrens #Syndrome #Rheumatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... Simultaneous clotting and bleeding ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
search for and treatment ... Presentation • Common Signs ... absent NK-cell activity ... Treatment Approach ... #Management #Hematology
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