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oncology differential cell classification management anemia cancer chronic cll emergencies eosinophil eosinophilia hemeonc hemolytic histiocytosis hodgkins langerhans lch leukemia lymphocytic
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... evaluation or workup ... glucocorticoid treatment ... #diagnosis #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential Diagnosis ... Algorithm Hodgkin ... Responsive to Treatment ... pathophysiology #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Algorithm • Sickle ... cells - Consider ... Consider RBC membrane disorder ... #Algorithm #workup ... #hematology #testing
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... lymphoproliferative disorders ... microglobulin Treatment ... #workup #oncology ... #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Algorithm Polycythemia ... Too many cells in ... : neuro, heme (bleeding ... #Algorithm #workup ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... classification #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... syndrome): - Hematologic ... Simultaneous clotting and bleeding ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... Biopsy: Solitary disorder ... EMD myeloma Diagnostic ... Bone marrow Treatment ... #Workup #Hematology
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
LCH is a rare disorder ... • Pulmonary Symptoms ... DIAGNOSIS • Imaging ... TREATMENT OPTIONS ... is crucial in pulmonary
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