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management differential oncology hemeonc latenttb syndrome tuberculosis abscess classification emergencies hemophagocytic hemophilia hlh hodgkins immune infections infectiousdiseases inflammatory iris leukemia
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Lymphoma • Lung cancer ... Active TB: • ... : Active TB: • ... #Diagnosis #Management ... #Treatment #ActiveTB
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Lymphoma • Lung cancer ... Active TB: • ... : Active TB: • ... #Diagnosis #Management ... #Treatment #ActiveTB
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... Individual factor activity ... center. ... #Management #treatment ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Tyrosine Kinase activity ... -> AML: Blast crises ... lymphoid organs When Cancer ... #Leukemia #Hematology ... #Oncology #Diagnosis
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Most common cause ... • Large volume feeding ... foreign body, cancer ... westermani • Other: TB ... Lung #Abscess #pulmonary
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• PET scan - activity ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... Hodgkins #lymphoma #diagnosis ... classification #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
increase in CD4+ cells ... , pulmonary infiltrates ... lymphadenitis, pulmonary ... , hypoxia, and pulmonary ... • Persistently active
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... , INC risk PE, Pulmonary ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... muscarinic agonists • Active
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Kansasii: • Mimics TB ... disease, alcohol, cancer ... bloodstream - seeding ... Hematologic malignancy
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... Simultaneous clotting and bleeding ... Treat underlying cause ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
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