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diagnosis hematology management syndrome algorithm anemia aplastic apml cardiology clinical criticalcare differential differentiation emergencies foamed heartfailure hemeonc icu mds myelodysplasia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
lymphadenopathy CML Findings ... develop leukostasis syndrome ... manifestations, hypoxia, CXR ... • Tumor lysis syndrome ... #Hematology #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are caused by bleeding ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... factors (examples: G-CSF ... diagnosis #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... - pulmonary opacities ... sepsis), PE, DAH, CHF ... management #hematology #oncology
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
Pathogenesis and clinical findings ... PO4& Mg prior to feeding ... overload -> - CHF ... - Pulmonary ... PO4 and Mg into cells
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... virus (EBV) • Leukemia ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Simultaneous clotting and bleeding ... interventional radiology ... Usually myeloid leukemias ... “big & sticky” cells ... renal failure, pulmonary
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Some exam findings ... with presence of pulmonary ... causing hypovolemia needing ... acute coronary syndrome ... #heartfailure #chf
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