14 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... - pulmonary opacities ... Diagnosis: >3 symptoms ... sepsis), PE, DAH, CHF ... management #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
lymphadenopathy CML Findings ... develop leukostasis syndrome ... manifestations, hypoxia, CXR ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Pathogenesis and clinical findings ... PO4& Mg prior to feeding ... overload -> - CHF ... - Pulmonary ... pathophysiology #symptoms
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... Simultaneous clotting and bleeding ... interventional radiology ... “big & sticky” cells ... renal failure, pulmonary
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... unusual bruising or bleeding ... are caused by bleeding ... factors (examples: G-CSF ... diagnosis #hematology #oncology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
or serologies + symptoms ... FINDINGS: • AAV ... capillaritis leading ... of DAH) RENAL FINDINGS ... diagnosis #management #treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... aplastic anemia Treatment ... • Improve the symptoms ... Aplastic #Anemia #oncology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
tissue: Epithelioid cells ... e.g. incidental CXR ... finding) ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... Paradoxical spontaneous bleeding ... Manifestations - Findings ... thrombophlebitis, pulmonary ... Antiphospholipid syndrome
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Some exam findings ... with presence of pulmonary ... causing hypovolemia needing ... acute coronary syndrome ... #heartfailure #chf