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diagnosis management oncology differential blood hemeonc latenttb product reactions rheumatology syndrome tb tuberculosis algorithm apml atlas bruising cancer causes classification
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Liver diseases ... , Bleeding gastric ... PD deficiency, Pulmonary ... coagulopathy (DIC ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Schistocytes, helmet cells ... • Severe Liver Disease ... Treatment: ... diagnosis #causes #treatment ... #management #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
screening for disease ... with established disease ... Individual factor activity ... by a hemophilia treatment ... #hematology
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
involvement - seeding ... and Culture • CXR ... Tuberculosis Treatment ... Initiating Treatment ... • Check CXR and
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Tyrosine Kinase activity ... manifestations, hypoxia, CXR ... Fibrinolysis & DIC ... #Leukemia #Hematology
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
involvement - seeding ... and Culture • CXR ... Tuberculosis Treatment ... Initiating Treatment ... • Check CXR and
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Willebrand factor activity ... ristocetin cofactor activity ... Warfarin • Acute DIC ... • Acute DIC • ... Differential #Diagnosis #Hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Paradoxical spontaneous bleeding ... with autoimmune diseases ... thrombophlebitis, pulmonary ... skin necrosis • DIC ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... common • Imaging: CXR ... - pulmonary opacities ... diagnosis #management #hematology
Differential diagnosis The table summarizes the most common diseases, that present with consolidation. Chronic diseases are indicated in
Chronic diseases ... - Cells - tumor ... respond to the treatment ... #Diagnosis #Radiology ... #Pulmonary #CXR
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