18 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Hyperviscosity Syndrome ... • Spontaneous bleeding ... neutrophil count < 500 cells ... #differential #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... by bleeding (petechiae ... Out Secondary Causes ... blood count with differential ... diagnosis #hematology #oncology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... maintained fever CAUSES ... hyperthermia crisis (late sign ... amphetamines) Toxic: • Radiologic ... #Hyperthermia #Differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... and petechiae Causes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC w differential ... Goodpasture's cause ... leading to diffuse ... #differential # ... diagnosis #management #treatment
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
• Mounier-Kuhn syndrome ... dyskinesia • Young syndrome ... Nasal polyps and signs ... mycobacteria Treatment ... #differential #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... initiation • Differential ... management #hematology #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Simultaneous clotting and bleeding ... Treat underlying cause ... interventional radiology ... “big & sticky” cells ... renal failure, pulmonary
Differential diagnosis
The table summarizes the most common diseases, that present with consolidation.
Chronic diseases are indicated in
- Cells - tumor ... lobar pneumonia caused ... respond to the treatment ... #Diagnosis #Radiology ... #Pulmonary #CXR
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of congestion ... with presence of pulmonary ... acute coronary syndrome ... the determined cause ... #diagnosis #differential