12 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Diagnosis Framework HEMATOLOGIC ... • Spontaneous bleeding ... neutrophil count < 500 cells ... #differential #
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... Liver diseases, Bleeding ... PD deficiency, Pulmonary ... key #diagnosis #differential ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... sepsis), PE, DAH, CHF ... diagnosis #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are caused by bleeding ... blood count with differential ... factors (examples: G-CSF ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
): - Hematologic ... Simultaneous clotting and bleeding ... interventional radiology ... “big & sticky” cells ... renal failure, pulmonary
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... vein: Budd-chiari syndrome ... , Congestion/CHF ... • Gilbert's syndrome ... RBC (hemolysis, bleeding
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... causing hypovolemia needing ... acute coronary syndrome ... #diagnosis #differential ... #heartfailure #chf
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... cardiomyopathy • Pulmonary ... May have typical HF ... Avoid Warfarin and DOAC ... #treatment
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... Multinucleated giant cells ... Cerebrospinal fluid (CSF ... #Diagnosis #Rheumatology