15 results
Direct-acting oral anticoagulants (DOACs) for VTE treatment and prevention - Comparison Table

#DOAC #Anticoagulants #Anticoagulation #VTE #Management
anticoagulants (DOACs ... ) for VTE treatment ... Comparison Table #DOAC ... Anticoagulants #Anticoagulation ... VTE #Management #Pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
patients on chronic anticoagulation ... interruption per treatment ... and procedural bleeding ... with a very low bleeding ... #pharmacology #
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... at high risk of bleeding ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... #Anticoagulation
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... for the treatment ... anticoagulants (DOACs ... #Cancer #Algorithm ... #Anticoagulation
Venous Thromboembolism Treatment Algorithm
Branch points: 
Active bleeding?  Active malignancy? Provoked?

- Dr. Joseph Shatzel
@Clotmaster

#Management #VTE #DVT
Thromboembolism Treatment ... Algorithm Branch ... points: Active bleeding ... Thromboembolism #Treatment ... #Hematology #Anticoagulation
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... thereby leading ... metabolization leading ... Interactions #Table #Pharmacology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... lead to severe bleeding ... #management #algorithm ... #pharmacology # ... treatment #medications
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... immunosuppressive meds ... • +/- Anticoagulation ... #management #pharmacology
A summary of the pharmacologic management of acute bleeding and secondary prevention of bleeds in LVAD
summary of the pharmacologic ... Thalidomide Danazol Anticoagulation ... #LVAD #Bleeding ... #Pharmacology # ... Management #Treatment
Anticoagulant Therapy after PCI (patients with AFib)
Dual-Therapy Preferred:
 • Triple therapy = increased bleeding
therapy = increased bleeding ... - Bleeding ... due to use of DOAC ... Triple #therapy #anticoagulation ... #PCI #pharmacology