37 results
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Abnormality • SLE ... Iron deficiency anemia ... #Secondary #dermatology ... #Differential #
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE ... ) Clinical Manifestations ... Demyelinating Syndrome ... , Seizure disorders
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... - Hemolytic anemia ... Associated - SLE ... #Diagnosis #hematology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... arthritis - (Reiter’s syndrome ... inflammation is secondary ... Erythematosus (SLE ... #msk #Differential
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... Chronic inflammatory disorders ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... Clinical Presentation ... Fever is the main clinical ... erythematosus [SLE ... with leukopenia, anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... - History of bleeding ... test, ANA (e.g., SLE ... changes), high MCV anemia ... #Differential #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... (SLE) General: ... Demyelinating syndromes ... ) Blood (75%): Anemia ... Thrombocytopenia #Lupus #SLE
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... , leading to the ... : • Clinical triad ... Type III Often Secondary ... (e.g. systemic
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
- Generalized Differential ... renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #dermatology #Differential