8 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Ig A vasculitis/HSP ... vasculitis - GPA ... Diagnosis #hematology ... #nonpalpable #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Maculopapular rash ... reticularis Differential ... #dermatology #rash
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Vasculitis - Collagen disorders ... #Differential # ... #dermatology #physicalexam
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
correlations • Purpura ... Identification of causes ... vasculitis (5%): PAN > GPA ... Vasculitis #dermpath #dermatology ... lesions #diagnosis #clinical
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Schonlein Leg Rash ... Tip: To differentiate ... #Legs #Rash #clinical ... #photo #dermatology ... #HSP
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... associated vasculitis - GPA
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... of shoulder and hip ... , mucositis • Rash ... tract, and often causes ... #Diagnosis #Rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Paradoxical spontaneous bleeding ... cryoglobulinemia Associated Disorders ... Skin necrosis • Purpura ... cryoglobulins • Negative causes ... #hematology