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diagnosis hepatology rheumatology syndrome dermatology lupus oncology sle systemic algorithm causes comparison erythematosus gastroenterology aflp autoimmune blood classification hodgkins lymphoma
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... disease, liver ... (DILI) Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... arthritis, Skin rash ... fraction < 20% Differential ... hepatomegaly, hepatitis ... #treatment #rheumatology
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... Supportive with treatment ... Liver transplant ... Hepatobiliary #hepatology ... #hepatitis #differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... • NASH, Chronic ... RBC (hemolysis, bleeding ... #differential # ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
of cholestatic disease ... disease: > 2 ... • NASH, Chronic ... RBC (hemolysis, bleeding ... chemistry #diagnosis #differential
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
from subclinical disease ... to acute liver ... (eg Viral) Management ... regarding need for treatment ... #Hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... #Disease #Pregnancy ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
infiltration) Differential ... Diagnosis: Viral Hepatitis ... Maternal Support - Critical ... #Pregnancy #hepatology ... obgyn #diagnosis #management
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... Cirrhosis/acute hepatitis ... sarcoidosis) • Liver ... Veno-occlusive disease
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... the spleen or liver ... Hepatosplenomegaly, cytopenias(bleeding ... involvement Differential ... #hematology
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