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diagnosis rheumatology hepatology syndrome dermatology oncology lupus sle systemic erythematosus gastroenterology hemophagocytic hlh lymphohistiocytosis summary activetb algorithm autoimmune blood causes
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... the spleen or liver ... Hepatosplenomegaly, cytopenias(bleeding ... • Other hematologic ... #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... arthritis, Skin rash ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... disease, liver ... Failure #Cirrhosis #Hepatology ... gastroenterology #management
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... cell lung CA, lymphoma ... • NASH, Chronic ... RBC (hemolysis, bleeding ... injury #hepatitis #differential
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... disorders (e.g. lymphoma ... thrombocythemia), Autoimmune disease ... #treatment #hematology ... #differential
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Maculopapular rash ... reticularis Differential ... • Angiocentric lymphoma ... #rash #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
of cholestatic disease ... disease: > 2 ... • NASH, Chronic ... RBC (hemolysis, bleeding ... chemistry #diagnosis #differential
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... DIC • Severe Liver ... Disease: - Impaired ... Treatment: ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Clinical Presentation ... number of sites of disease ... Treatment • Early ... classification #hematology ... #oncology #management
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