72 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
syndrome, Increased ... , Liver diseases ... , Bleeding gastric ... key #diagnosis #differential ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... arthritis, Skin rash ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... disease, liver ... Failure #Cirrhosis #Hepatology ... gastroenterology #management
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... vein: Budd-chiari syndrome ... • NASH, Chronic ... • Gilbert's syndrome ... RBC (hemolysis, bleeding
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
of invasive GAS disease ... (2+): kidneys, liver ... erythematous macular rash ... #STSS #treatment ... #management #diagnosis
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... thrombocythemia), Autoimmune disease ... #treatment #hematology ... #differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
disease: > 2 ... • NASH, Chronic ... RBC (hemolysis, bleeding ... • Gilbert's syndrome ... chemistry #diagnosis #differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... the spleen or liver ... Hepatosplenomegaly, cytopenias(bleeding ... involvement Differential ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... von Willebrand syndrome ... deficiency • Liver ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology