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diagnosis algorithm liver management lfts transaminitis acute causes gastroenterology oncology aclf anemia aplastic autoimmune bariatric bypass chemistry chronic cirrhosis complications
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... AST:ALT > 2.5 - Alcoholic ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential ... HSV • Toxic: Alcohol ... #Differential # ... Acute #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... • NAFLD • Alcohol ... • Drugs • AIH ... hepatitis • Drugs ... Others #LFTs #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Failure Infections Alcohol-Associated ... Hepatitis (AAH) ... Drug-Induced Liver Injury ... Failure #Cirrhosis #Hepatology
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... survival in severe AH ... #Hepatitis #Management ... #Algorithm #treatment ... #hepatology
Alcoholic Hepatitis - Summary Overview - Epidemiology - Pathophysiology - Clinical Features - Labs - Diagnosis - Differential Diagnosis - Treatment Sarah Onorato @sonorato11 #Alcoholic
Alcoholic Hepatitis ... - Diagnosis - Differential ... Diagnosis - Treatment ... sonorato11 #Alcoholic ... #Hepatitis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential ... • Infections: Hepatitis ... Drugs (MDMA), Alcohol ... Diagnosis #hepatology ... Transaminitis #LFTs #hepatitis
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... pattern of liver injury ... If suspected, AIH ... regarding need for treatment ... #Management #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... Diagnosis #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... ALT Ratios: • Alcoholic ... RBC (hemolysis, bleeding ... #hepatitis #differential ... diagnosis #algorithm #hepatology
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