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diagnosis algorithm management anemia anticoagulation aplastic cancer causes chemotherapy classification cyp3a4 disorders hodgkins inducers inhibitors interactions lymphoma malignancy myelodysplasia myelodysplastic
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
) Cancer-treatment ... thereby leading ... metabolization leading ... #Chemotherapy #Oncology ... #Hematology #Interactions
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... blood loss, Acute hemolysis ... Rebound effect from treatment ... Diagnosis #Algorithm #hematology
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
at high risk of bleeding ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology ... #Oncology
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
/uL Initial Workup ... ↑ Destruction (hemolysis ... Matthew Ho, MD ... Diagnosis #Algorithm #hematology ... #workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... - History of bleeding ... Infection exposure (l MD ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... Hypocellular/Hypoplastic MDS ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... are caused by bleeding ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
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