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rheumatology algorithm anemia differential hepatology management antibody approach atlas autoimmune basics blanching bruise comparison congenital criticalcare cryofibrinogenemia cryoglobulinemia cryoglobulins dermatology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia 1) DIAGNOSE ... haptoglobin ↑ indirect bilirubin ... Coombs • IgG type ... ± C3d • Blood ... 2) LOOK FOR a cause
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Algorithm Blood ... Increased Unconjugated Bilirubin ... Non-lmmune #Anemia #Classification ... #Algorithm #Causes ... #Hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Syndromes: • Type ... and stress may cause ... in the blood ... #hepatology #diagnosis ... #gastroenterology
Von Willebrand Disease Classification Type 1 (Accounts for ~3/4 of cases): • Defect: Quantitative defect (i.e. not
Willebrand Disease Classification ... for ~3/4 of cases ... VonWillebrand #Disease #Classification ... #Types #diagnosis ... #hematology
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
ecchymosis) is caused ... biliverdin and bilirubin ... at > 2 weeks Type ... Diagnosis VWF ... differentiate VWD type
Shock Classification Types - Pathophysiology Comparison Obstructive Shock: • Obstructive shock is characterized by a blockage in
Shock Classification ... Types - Pathophysiology ... a blockage in blood ... flow caused by ... #criticalcare #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... #types #classification ... #rheumatology #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... by bleeding (petechiae ... Out Secondary Causes ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular Causes ... RBC (hemolysis, bleeding ... intestines, white blood ... #differential #diagnosis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Pager Summary Type ... type and detects ... coagulopathy & ↑bleeding ... #Transfusions #diagnosis ... #management #hematology
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