13 results
Disorders of the Hepatic and Mesenteric Circulation

Platelets in Cirrhosis
Hypercoagulability in Cirrhosis
Bleeding in Cirrhosis
Portal Vein Thrombosis (PVT)
Mesenteric
Platelets in Cirrhosis ... Hypercoagulability in Cirrhosis ... Bleeding in Cirrhosis ... Circulation #Disorders #Hepatology ... #Gastroenterology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
non-ICU vs ICU causes ... Hyperbilirubinemia #direct #bilirubin ... Diagnosis #Algorithm #gastroenterology ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
to non-cirrhotic ... function: INR, bilirubin ... Post-Hepatic: • Cardiac causes ... Differential #Diagnosis #causes ... #hepatology
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... brown: elevated bilirubin ... chylous ascites), bilirubin ... Differential #Diagnosis #hepatology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
dL) 1 Liver (cirrhosis ... , bilirubin >2x, ... S Stroke 1 B Bleeding ... AFib #Diagnosis #Hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
birth with serum bilirubin ... associated with bilirubin ... and stress may cause ... #hepatology #diagnosis ... #gastroenterology
Preventing Decompensation in Cirrhosis 

cACLD, CSPH, and the Rule of Five
Prevention of Decompensation
Nonselective Beta Blockers (NSBB)
Preventing
Decompensation in Cirrhosis ... Preventing recurrent bleeding ... Decompensation #Cirrhosis ... treatment #management #hepatology ... #gastroenterology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... intralobular bile ducts causes ... cholestasis → Cirrhosis ... slightly elevated • Bilirubin ... diagnosis #workup #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
week • Direct bilirubin ... hepatitis: < 1 • Cirrhosis ... Elevation: • Bilirubin ... RBC (hemolysis, bleeding ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... week • Direct bilirubin ... hepatitis: < 1 • Cirrhosis ... RBC (hemolysis, bleeding ... diagnosis #algorithm #hepatology