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diagnosis rheumatology treatment erythematosus lupus syndrome systemic achalasia cardiology cardiomyopathy cerebritis classification cns cryofibrinogenemia cryoglobulinemia cryoglobulins dermatology esophageal esophagus hemophagocytic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Summary • Epidemiology ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... , Seizure disorders ... autoantibodies that will cause ... cerebritis #diagnosis #management
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... immune system, leading ... • They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Autoimmune diseases: SLE ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Summary ... Paradoxical spontaneous bleeding ... cryoglobulinemia Associated Disorders ... cryoglobulins • Negative causes ... #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... chronic inflammatory disorder ... Autoinflammatory disorder ... Rule out other causes ... #diagnosis #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Summary A defect ... a gas exchange disorder ... lung disease Caused ... shunt (Type 2) Clinical ... #treatment #hepatology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Cardiomyopathy - Summary ... exclude other causes ... Clinical • Under-recognized ... orthopnea, PND, LE ... Period • Breast-feeding
Achalasia Summary Epidemiology: 10 cases per 100,000 individuals Defined by inadequate relaxation of the LES and aperistalsis Primary or
Achalasia Summary ... Neurodegenerative disorders ... Chagas disease) Clinical ... Achalasia #diagnosis #management ... #treatment #gastroenterology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
body (Autoimmune disorder ... the most common clinical ... such as: • SLE ... Diagnosis: • Clinical ... #diagnosis #management
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