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diagnosis rheumatology lupus systemic management workup activation ana antibodies antinuclear arthritis cerebritis chronic classification cll cns cryoglobulinemia cryoglobulins differential disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... Demyelinating Syndrome ... , Seizure disorders ... inflammation, leading ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... Malignancy (e.g. hematologic ... ) • Endocrine disorders ... Clinical Features ... lymphopenia, low PLT • Anemia
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... : • Clinical triad ... diseases: - 10% SLE ... systemic lupus erythematosus ... (SLE), rheumatoid
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Systemic Lupus (SLE ... Demyelinating syndromes ... ) Blood (75%): Anemia ... #systemic #erythematosus
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Syndrome (SS), ... Arthritis, Sjögren Syndrome ... Lymphoproliferative Disorders ... ANA #patterns #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... purpura to mucosal bleeding ... [SLE], AOSD) • ... with leukopenia, anemia ... Diagnosis #Management #Hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Systemic lupus erythematosus ... the presence of anemia ... metabolic or endocrine disorders ... ANA and RF (if clinical
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Orange or Hep C Clinical ... lymphoproliferative disorders ... • Neutropenia, anemia ... workup #oncology #hematology
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