13 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... - History of bleeding ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Fibrinolysis → End ... organ damage Clinical ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... ecchymoses, mucosal bleeding ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... with leukopenia, anemia ... Activation #Syndrome #Diagnosis ... #Management #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... inflammation, leading ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
the most common cause ... , leading to infarction ... angular gyrus Clinical ... #Agraphia #clinical ... #neurology #diagnosis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... • Pernicious anemia ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
invasive procedures/ bleeding ... the Journal of Clinical ... reasoning during clinical ... It's time to end ... other than GI bleeding
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... Labs/Diagnosis:
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... systemic complaints- anemia ... identifies 85 to 95% of cases ... them, but urgent rheumatology