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diagnosis management oncology rheumatology activation aplastic classification cryoglobulinemia cryoglobulins dic differential disseminated emergencies hemeonc infections infectiousdiseases intravascular macrophage mas mycobacteria
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Fibrinolysis → End ... organ damage Clinical ... Treat primary cause ... #diagnosis #causes ... treatment #management #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... Petechial or purpuric rash ... with leukopenia, anemia ... Diagnosis #Management #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Clinical Presentation ... ecchymoses, mucosal bleeding ... and petechiae Causes ... #oncology #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... endothelial injury and end-organ ... • They can cause ... Cryoglobulins Cause ... : • Clinical triad
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
): - Hematologic ... intravascular coagulation ... Simultaneous clotting and bleeding ... Treat underlying cause ... - CRS: fever, rash
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Lady Windermere Syndrome ... : • Syndrome of ... Hematologic malignancy ... Bone Marrow - Anemia
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