12 results
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... disorder Clinical ... bruising • Skin ... bleeding from mucosal ... Disease #Diagnosis #Hematology
Staphylococcal Scalded Skin Syndrome (SSSS)

A 5-year-old girl presents to the ED with a rash that started
Staphylococcal Scalded Skin ... presents to the ED ... Syndrome #SSSS #Clinical ... #Photo #Peds #Pediatrics ... #Dermatology
Raynaud's in Dark Skin
In general for darker skin, most aspects of the skin exam stay constant
Raynaud's in Dark Skin ... aspects of the skin ... #dermatology #brown ... #clinical #photos ... #hands #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Paradoxical spontaneous bleeding ... Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Findings: • Bleeding ... Fibrinolysis → End ... organ damage Clinical ... Findings: • Bleeding ... treatment #management #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... Hepatosplenomegaly, cytopenias(bleeding ... Lymphomas • Other hematologic ... Malignancies (eg ... #differential #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... - Purpura - Skin ... Syndrome: • Clinical ... reticularis & skin ... classification #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... purpura to mucosal bleeding ... Diagnosis #Management #Hematology ... #Rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... Headaches • Pale skin ... ecchymoses, mucosal bleeding ... Anemia #oncology #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... in Evaluating Bleeding ... haemophilias, bleeding ... and skin haemorrhage ... pediatrics #diagnosis #hematology