13 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... (DILI) Viral Hepatitis ... Procedures Management ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
syndrome - Veno-occlusive ... - Alcoholic hepatitis ... fibrosis - Acute ... fatty liver of ... #differential #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Albumin Gradient (SAAG ... - Alcoholic hepatitis ... thrombosis - Veno-occlusive ... disease - Acute ... Differential #Diagnosis #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
HTN: ascites (SAAG ... • Cirrhosis/acute ... hepatitis • Infiltrative ... Schistosomiasis • Veno-occlusive ... Diagnosis #causes #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... viral hepatitis ... Chronic viral hepatitis ... RBC (hemolysis, bleeding ... #differential #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... Diagnosis: Viral Hepatitis ... #Pregnancy #hepatology ... obgyn #diagnosis #management
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Chronic viral hepatitis ... RBC (hemolysis, bleeding ... #injury #hepatitis ... diagnosis #algorithm #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... liver failure ... hepatocellular pattern of liver ... (eg Viral) Management ... #Hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... > 3 mg/dL) or acute ... liver failure ... #Indications #management ... #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Findings: • Bleeding ... malignancy (Especially acute ... DIC • Severe Liver ... causes #treatment #management ... #hematology