9 results
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Epidermal Necrolysis (TEN ... is a clinical dermatological ... #TEN #Dermatology ... #PhysicalExam #Video ... #Clinical #SJS
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
Leser–Trélat Sign ... paraneoplastic sign ... #LeserTrelat #Sign ... #PhysicalExam #clinical ... #video #skin #dermatology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
Tubulointerstitial nephritis • Skin ... involvement with bleeding ... Prerenal azotemia • Skin ... #comparison #table ... #dermatology
Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign")

Asboe-Hansen sign is the extension
evaluation of TEN ... #PhysicalExam #Video ... #Clinical #Bullae ... #Blister #Dermatology ... #skin
Petechiae on Physical Exam

Pinpoint, round spots that appear on the skin as a result of microscopic
appear on the skin ... of microscopic bleeding ... #PhysicalExam #dermatology ... #foot #skin #clinical ... #video
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... Autoimmune diseases • Clinical ... Infections (HIV, EN ... Hepatosplenomegaly, cytopenias(bleeding ... #differential #hematology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... ulcerations • Skin ... auricular papules Clinical ... Phenotype 2 • Men ... #dermatology #diagnosis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Paradoxical spontaneous bleeding ... Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... Biopsy: Typical pathologic ... #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... in Evaluating Bleeding ... acquired rather then ... and skin haemorrhage ... pediatrics #diagnosis #hematology