11 results
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Purpura Clinical ... Menorrhagia • GI bleeding ... only for severe bleeding ... #Diagnosis #Overview ... #Hematology
Petechiae: punctate spots that arise from spontaneous bleeding secondary to profound thrombocytopenia. 
The spots (easily visible
from spontaneous bleeding ... secondary to profound thrombocytopenia ... UCSD Catalog of Clinical ... Images #Clinical ... #Photo #Dermatology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... disorder Clinical ... platelet count (mild thrombocytopenia ... VonWillebrand #Disease #Diagnosis ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... - History of bleeding ... epistaxis, gingival bleeding ... menstrual - Recent procedures ... Causes #Workup #hematology
Chondrodermatitis nodularis 
 - Scaly papule on ear, usually helix 
 - Painful, especially when sleeping
especially when sleeping ... Chondrodermatitis #Nodularis #Dermatology ... #Diagnosis #Benign ... #Clinical #Photo
Seborrheic keratosis 
 - Well-circumscribed, stuck-on appearance 
 - Waxy texture 
 - Verrucous surface
rapid growth, or bleeding ... Seborrheic #Keratosis #Dermatology ... #Diagnosis #Benign ... #Clinical #Photo
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
transfusion • Thrombocytopenia ... organ damage Clinical ... coagulopathy - Thrombocytopenia ... #Coagulation #diagnosis ... treatment #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... infections/fevers • Thrombocytopenia ... ecchymoses, mucosal bleeding ... Anemia #oncology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... purpura to mucosal bleeding ... leukopenia, anemia, and thrombocytopenia ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... in Evaluating Bleeding ... Previous surgical procedures ... peds #pediatrics #diagnosis ... #hematology #primarycare