16 results
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Purpura Clinical ... Menorrhagia • GI bleeding ... Intracranial hemorrhage Management ... only for severe bleeding ... Diagnosis #Overview #Hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... TMA: Unexplained thrombocytopenia ... Reticulocytes, smear ... MAHA likely: • Smear ... #Algorithm #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... disorder Clinical ... • Prolonged bleeding ... platelet count (mild thrombocytopenia ... Disease #Diagnosis #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... peripheral blood smear ... dysplasia on the smear ... Causes #Workup #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
transfusion • Thrombocytopenia ... organ damage Clinical ... • Peripheral smear ... causes #treatment #management ... #hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
diagnosis and initial management ... based primarily on clinical ... #Diagnosis #Management ... #Hematology #HIT ... Heparin #Induced #Thrombocytopenia
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Peripheral smear ... immunophenotype Clinical ... with anemia or thrombocytopenia ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... Diagnosis: • Clinical ... Management: • ... non-heparin A/C if clinical ... #Treatment #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... leukopenia, anemia, and thrombocytopenia ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... infiltrates (anemia, thrombocytopenia ... • Peripheral smear ... • Significant bleeding ... #Leukemia #Hematology