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diagnosis management oncology monkeypox photo product reactions rheumatology algorithm antimda5 antimda5dm aplastic atlas basics coagulation cryofibrinogenemia dermatomyositis dic differential disseminated
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... Mycosis fungoides (cutaneous ... • Bleomycin Hematologic ... • Sickle Cell Anemia ... #dermatology #Differential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... violaceous, nontender cutaneous ... CLL -> Invade Skin ... #Leukemia #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... organ damage Clinical ... involvement (2%) Cutaneous ... Treat primary cause ... treatment #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... unusual bruising or bleeding ... just beneath the skin ... by bleeding (petechiae ... Syndromes #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... Headaches • Pale skin ... and petechiae Causes ... result from low blood ... #oncology #hematology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... scabitic mite or by cutaneous ... bruise') is where bleeding ... dilatation of small cutaneous ... #Diagnosis #Dermatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
DERMATOMYOSITIS Cutaneous ... ulcerations • Skin ... auricular papules Clinical ... onset [33-74%] • Blood ... #dermatology #diagnosis
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
trauma, aplastic anemia ... steroid use Dx: skin ... hyphae invading blood ... Mucormycosis #Eschar #dermatology ... #skin #clinical
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
which can plug blood ... Paradoxical spontaneous bleeding ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... include: fever, cutaneous ... coagulopathy & ↑bleeding ... infections with skin ... diagnosis #management #hematology
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