12 results
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
is a clinical dermatological ... differentiating between the diagnosis ... #TEN #Dermatology ... #PhysicalExam #Video ... #Clinical #SJS
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... • Goodpasture syndrome ... vasculitis (inflamed blood ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... Petechial or purpuric rash ... #Diagnosis #Management ... #Hematology #Rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... , breast CA - Hematologic ... neutrophils in the blood ... #diagnosis #dermatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... auricular papules Clinical ... onset [33-74%] • Blood ... #dermatology #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand
70 M vertebral osteomyelitis on vancomycin and cefepime for
diffuse palpable rash ... Diagnosis? ... Churg-Strauss syndrome ... Vasculitis #LCV #Hand #skinrash ... #dermatology #clinical
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
which can plug blood ... Paradoxical spontaneous bleeding ... : • + Clinical ... Antiphospholipid syndrome ... hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... workup #oncology #hematology