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diagnosis oncology management cancer clinical dress leukemia activation algorithm aplastic canimorsus capnocytophaga chronic cll comparison differential friction injury lymphocytic macrophage
DRESS Syndrome vs SJS/TEN DRESS • Latency: 2-8 weeks • Rash: Morbilliform • Mucosal involvement: 50% have
DRESS Syndrome vs ... : 2-8 weeks • Rash ... : 4-28 days • Rash ... involvement with bleeding ... comparison #table #dermatology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic M - Malignancy: Leukemia cutis,
Approach to the Rash ... Dermatoses: Sweet Syndrome ... Gangrenosum, NEH T - Treatment ... dermatoses #skin ... MINTC #Mnemonic #dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Headaches • Pale skin ... ecchymoses, mucosal bleeding ... Treatment: ... #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... , breast CA - Hematologic ... Treatment: - Systemic ... #diagnosis #dermatology
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Capnocytophaga Canimorsus Skin ... Bandemia, AKI. ... Diffuse blanching ... colonize human skin ... #Rash #dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... just beneath the skin ... are caused by bleeding ... factor (GCSF) treatments ... #diagnosis #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
rash in association ... Skin involvement ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... Petechial or purpuric rash ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... • Neutropenia, anemia ... microglobulin Treatment ... • Richter’s Syndrome ... workup #oncology #hematology
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