13 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
and bridging for VTE ... Clotmaster #VTE ... #DOAC #Bridging ... Anticoagulant #Anticoagulation ... #Pharmacology #Hematology
Venous Thromboembolism Treatment Algorithm
Branch points: 
Active bleeding?  Active malignancy? Provoked?

- Dr. Joseph Shatzel
@Clotmaster

#Management #VTE #DVT
Thromboembolism Treatment ... points: Active bleeding ... #Management #VTE ... Thromboembolism #Treatment ... #Hematology #Anticoagulation
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
) and IMPROVE (VTE ... validated for VTE ... treatment, only ... of withholding anticoagulation ... #Factors #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... body mass index; VTE ... #DOAC #VTE #Malignancy ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Fibrillation, VTE ... Prophylaxis, VTE ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
for VTE in Malignancy ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
Lower Extremity Venous Thrombosis - Management and Anatomy

Deep - Superficial - Active Bleeding

#LowerExtremity #Veins #Venous #Thrombosis
Superficial - Active Bleeding ... Superficial #Deep #VTE ... #DVT #Hematology ... Management #Anatomy #Anticoagulation
Algorithm for the Long-Term Treatment of Venous Thromboembolism 

Reference: https://doi.org/10.1182/blood.2019002364

by Dr. Clive Kearon and Dr. Susan
the Long-Term Treatment ... #LongTerm #Treatment ... Thromboembolism #VTE ... #Anticoagulation ... #Algorithm #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... lead to severe bleeding ... #pharmacology #treatment ... decisionaid #cardiology #hematology