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leukemia management hemeonc lymphocytic algorithm cancer differentiation emergencies essential et mds myelodysplasia myelodysplastic oncologic syndrome syndromes thrombocythemia workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... Chronic leukemia ... • Malaise, bleeding ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Diagnosis: • ... microglobulin Treatment ... #workup #oncology ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... • Induce blast cell ... Renal Failure Treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... uw_IMresidency #CLL ... #Leukemia #oncology ... #hematology #hemeonc
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... Marrow Failure • Chronic ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... syndrome): - Hematologic ... Simultaneous clotting and bleeding ... ± tocilizumab; call ... #HemeOnc #Diagnosis
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
(ET) ET is a chronic ... PV, MDS, CML) Treatment ... transformation into MDS or AML ... Thrombocythemia #ET #hematology ... #hematology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... median age at diagnosis ... with repeated red cell ... an infection or bleeding ... #algorithm #hematology
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