10 results
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
and DOACs VKA, ... , Rivaroxaban, Apixaban ... , Edoxaban, Betrixaban ... anticoagulant ... #Switching #hematology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #DOAC #Bridging ... Anticoagulation #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban ... #Pharmacology #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... Currently, edoxaban ... body mass index; VTE ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... (Praxbind) - Apixaban ... Betrixaban (Bevyxxa), Edoxaban ... anticoagulation #doac ... #hematology #reversal
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Renal Dosing: Apixaban ... if CrCl < 50) Edoxaban ... @Bloodman #DOAC ... Anticoagulation #Hematology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
for VTE in Malignancy ... **Edoxaban is initiated ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... treatment; volume ... Antidotes: • Apixaban ... , Edoxaban or Rivaroxaban ... #hematology #management
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... Edoxaban, rivaroxaban ... , and apixaban are ... Rivaroxaban and apixaban ... Chemotherapy #Oncology #Hematology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
interruption per treatment ... and procedural bleeding ... with a very low bleeding ... inhibitor) • Apixaban ... , Edoxaban, Rivaroxaban
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
of Direct Oral Anticoagulants ... , rixaroxaban, apixaban ... and edoxaban. ... thrombin time #doac ... #hematology #laboratory