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diagnosis blood oncology reactions activation aflp aplastic atlas causes coagulation differential disseminated fatty hepatic intravascular key laboratory leukemia liver liverfailure
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... Liver diseases, Bleeding ... cells - G-6-PD deficiency ... coagulopathy (DIC ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation (DIC ... Manifestations of DIC ... thrombopoietin deficiency ... causes #treatment #management ... #hematology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
of fibrin-split products ... As a result of DIC ... thrombopoietin deficiency ... - Anemia - Bone ... LiverFailure #Hepatic #Hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
acid metabolism products ... nausea, vomiting, abdominal ... rapidly develops (DIC ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology ... #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... recipients w/ IgA deficiency ... coagulopathy & ↑bleeding ... Transfusions #diagnosis #management ... #hematology #reactions
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, weight loss, abdominal ... night sweats, bleeding ... - infiltrates (anemia ... Fibrinolysis & DIC ... #Leukemia #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... with leukopenia, anemia ... Fibrin degradation products ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... recipients w/ IgA deficiency ... coagulopathy & ↑bleeding ... Transfusion #diagnosis #management ... #hematology #reactions
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