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diagnosis management anemia myelodysplastic product reactions treatment algorithm cancer chronic cll lymphocytic myelodysplasia syndrome syndromes transfusion transfusions workup
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... Can progress to MDS ... or acute leukemia ... management #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... transformation to acute leukemia ... Myelodysplastic #Syndrome #MDS ... Management #treatment #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... blast cells - Blood ... , weight loss, abdominal ... #Hematology #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... virus (EBV) • Leukemia ... result from low blood ... #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Lymphocytosis: Absolute blood ... Pure red cell aplasia ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... Causes • Anemia • Aplastic ... • Hairy Cell Leukemia ... Syndromes #diagnosis #hematology ... #oncology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Injury (TRALI): Leading ... due to marrow aplasia ... coagulopathy & ↑bleeding ... by Nick Mark MD ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... due to marrow aplasia ... coagulopathy & ↑bleeding ... infographic by Nick Mark MD ... diagnosis #management #hematology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
From Blood Cancer ... hematopoiesis resulting in blood ... acute myeloid leukemia ... an infection or bleeding ... #algorithm #hematology
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